Clozaril vs. Seroquel

• Are Clozaril and Seroquel the Same Thing?
• What Are Possible Side Effects of Clozaril?
• What Are Possible Side Effects of Seroquel?
• What Is Clozaril?
• What Is Seroquel?
• What drugs interact with Clozaril?
• What drugs interact with Seroquel?
• How Should Clozaril Be Taken?
• How Should Seroquel Be Taken?

Clozaril (clozapine) and Seroquel (quetiapine) are antipsychotic medications used to treat schizophrenia.

Clozaril is also used to help reduce the risk of suicidal behavior in people with schizophrenia or similar disorders.

Seroquel is also used to treat major depression and bipolar disorder.

Side effects of Clozaril and Seroquel that are similar include constipation, sleep problems, weight gain, dry mouth, drowsiness, dizziness, or headache.

Side effects of Clozaril that are different from Seroquel include drooling (especially at night), increased sweating, blurred vision, spinning sensation, or shaking (tremor).

Side effects of Seroquel that are different from Clozaril include mood or behavior changes, stomach pain, upset stomach, nausea, vomiting, lightheadedness, tiredness, sore throat, breast swelling or discharge, missed menstrual periods, or increased appetite.

Both Clozaril and Seroquel may interact with alcohol, antipsychotic medications, antidepressants, antibiotics, HIV/AIDS medications, anti-malaria medications, narcotics, antifungals, heart or blood pressure medications, St. John's wort, or seizure medications.

Clozaril may also interact with armodafinil, modafinil, arsenic trioxide, bosentan, cimetidine, conivaptan, dexamethasone, nefazodone, imatinib, isoniazid, barbiturates, tacrolimus, atropine, belladonna, clidinium, dicyclomine, scopolamine, medicines to prevent or treat nausea and vomiting, migraine headache medicines.

Seroquel may also interact with heart rhythm medicines, cancer medications, other drugs that make you sleepy or slow your breathing (sleeping pills, prescription cough medicines, muscle relaxers, or anxiety medicines), or tuberculosis medicines.

Do not stop using Clozaril suddenly or you could have unpleasant withdrawal symptoms.

Side effects of Clozaril include:

• dry mouth or throat
• headache
• blurred vision
• drowsiness
• dizziness
• fatigue
• loss of appetite
• stomach pain
• nausea
• diarrhea
• constipation
• gas, or
• muscle weakness.

• fever,
• hot flashes,
• sensitivity to heat,
• sweating,
• headache,
• nervousness,
• irritability,
• nausea,
• sleep problems (insomnia),
• changes in appetite or changes in weight,
• changes in menstrual perdiods,
• and temporary hair loss.

Clozaril (clozapine) is an antipsychotic medication that is used to treat severe schizophrenia symptoms in people who have not responded to other medications. Clozaril is also used to help reduce the risk of suicidal behavior in people with schizophrenia or similar disorders.

Seroquel (quetiapine) is a psychotropic medication used to treat schizophrenia in adults and children who are at least 13 years old. Seroquel is also used in the treatment of major depression and bipolar disorder.

Clozaril may interact with other medicines that can make you sleepy or slow your breathing (such as cold or allergy medicines, narcotic pain medicines, sleeping pills, muscle relaxers, and medicines for depression, seizure, anxiety), and heart or blood pressure medications. Clozaril may also interact with alcohol, other antipsychotic medications, armodafinil, modafinil, arsenic trioxide, bosentan, cimetidine, conivaptan, dexamethasone, nefazodone, imatinib, isoniazid, phenobarbital and other barbiturates, St. John's wort, tacrolimus, antibiotics, antifungals, anti-malaria medications, atropine, belladonna, clidinium, dicyclomine, scopolamine, heart or blood pressure medications, HIV/AIDS medications, medicines to prevent or treat nausea and vomiting, and migraine headache medicines.

Seroquel may interact with many different drugs. Tell your doctor all medications and supplements you use.

For most patients, the recommended dose of Clozaril is 5 mg three times a day. Based on individual patient response, the dose may be increased to 10 mg three times a day. Use of Clozaril for periods longer than two or three weeks is not recommended.

Dosing preparations are 25, 50, 100, 200, 300, and 400 mg tablets.