Brintellix (Trintellix) vs. Prozac

Brintellix (vortioxetine) and Prozac (desvenlafaxine) are antidepressants used to treat major depressive disorder (MDD).

The brand name Brintellix was changed to Trintellix in June 2016 because of confusion with the name of an antiplatelet drug called Brilinta (ticagrelor).

Brintellix (Trintellix) and Prozac are different types of antidepressants. Brintellix is a serotonin modulator and Prozac is a selective serotonin and norepinephrine reuptake inhibitor (SNRI).

Side effects of Brintellix (Trintellix) and Prozac that are similar include nausea, constipation, sexual dysfunction (such as decreased sex drive, impotence, or difficulty having an orgasm), dry mouth, or dizziness.

Side effects of Brintellix (Trintellix) that are different from Prozac include diarrhea, vomiting, gas, abnormal dreams, and itching.

Side effects of Prozac that are different from Brintellix (Trintellix) include increased or excessive sweating, drowsiness, sleep problems (insomnia), loss of appetite, tightness in your jaw, weight loss, blurred vision, or nervousness.

Both Brintellix (Trintellix) and Prozac may interact with other antidepressants, tramadol, tryptophan, or seizure medications.

Brintellix (Trintellix) may also interact with monoamine oxidase inhibitors (MAOIs), triptans, buspirone, quinidine, or rifampicin.

Common side effects of Brintellix (Trintellix) include:

• nausea
• diarrhea
• dry mouth
• constipation
• vomiting
• gas
• dizziness
• abnormal dreams
• itching, and
• decreased sexual desire

Antidepressants such as Brintellix (Trintellix) increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies. Tell your doctor if you experience any thoughts of suicide while taking Brintellix (Trintellix).

Common side effects of Prozac include:

• nausea,
• upset stomach,
• constipation,
• headaches,
• anxiety,
• sleep problems (insomnia),
• drowsiness,
• dizziness,
• nervousness,
• heart palpitations,
• loss of appetite or increase in appetite,
• weight changes,
• cold symptoms (stuffy nose, sneezing, sore throat),
• dry mouth,
• decreased sex drive,
• impotence, or
• difficulty having an orgasm.

Brintellix (Trintellix) (vortioxetine) tablets are an antidepressant indicated for the treatment of major depressive disorder (MDD).

Prozac is a prescription medicine used to treat depression. It is important to talk with your healthcare provider about the risks of treating depression and also the risks of nottreating it. You should discuss all treatment choices with your healthcare provider.

Prozac is used to treat:

• Major Depressive Disorder (MDD)
• Obsessive Compulsive Disorder (OCD)
• Bulimia Nervosa*
• Panic Disorder*
• Depressive episodes associated with Bipolar I Disorder, taken with olanzapine (Zyprexa)
• Treatment Resistant Depression (depression that has not gotten better with atleast 2 other treatments), taken with olanzapine (Zyprexa)*

*Not approved for use in children

Talk to your healthcare provider if you do not think that your condition is getting betterwith Prozac treatment.

Brintellix (Trintellix) may interact with monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), triptans, buspirone, tramadol, tryptophan products, NSAIDs, aspirin, warfarin, bupropion, fluoxetine, paroxetine, quinidine, rifampicin, carbamazepine, and phenytoin. Tell your doctor all medications and supplements you use.

Prozac may interact with cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, medicine for seizures or anxiety, monoamine oxidase inhibitors (MAOIs), nonsteroidal anti-inflammatory drugs (NSAIDs), other antidepressants, blood thinners, or migraine headache medicines.

Prozac may also interact with alprazolam, clopidogrel, clozapine, flecainide, haloperidol, nebivolol, vinblastine, or seizure medications.

Withdrawal symptoms may occur if you suddenly stop taking Prozac.

The recommended starting dose of Brintellix (Trintellix) is 10 mg administered orally once daily without regard to meals. Dosage should then be increased to 20 mg/day, as tolerated.

Take Prozac exactly as prescribed. Your healthcare provider may need to change the dose of Prozac until it is the right dose for you.

Prozac may be taken with or without food.

If you miss a dose of Prozac, take the missed dose as soon as you remember.If it is almost time for the next dose, skip the missed dose and take your nextdose at the regular time. Do not take two doses of Prozac at the same time.

If you take too much Prozac, call your healthcare provider or poison control center right away, or get emergency treatment.