Cipro vs. Atridox, Doryx (doxycycline hyclate)

• Are Doxycycline Hyclate and Cipro the Same Thing?
• What Are Possible Side Effects of Cipro?
• What Are Possible Side Effects of Doxycycline Hyclate?
• What Is Cipro?
• What Is Doxycycline Hyclate?
• What Drugs Interact with Cipro?
• What Drugs Interact with Doxycycline Hyclate?
• How Should Cipro Be Taken?
• How Should Doxycycline Hyclate Be Taken?

Cipro (ciprofloxacin) and doxycycline hyclate are antibiotics prescribed to treat a variety of infections caused by susceptible bacteria.

Doxycycline hyclate is also used as adjunctive therapy in acute intestinal amebiasis and severe acne, and for prophylaxis of malaria.

Cipro and doxycycline hyclate are different types of antibiotics. Cipro is a quinolone antibiotic and doxycycline hyclate is a tetracycline antibiotic.

Brand names for doxycycline hyclate include Oracea, Monodox, and Doryx.

Side effects of Cipro and doxycycline hyclate that are similar include diarrhea, nausea, vomiting, and rash.

Side effects of Cipro that are different from doxycycline hyclate include dizziness, drowsiness, headache, stomach upset, abdominal pain, blurred vision, nervousness, anxiety, agitation, and sleep problems (insomnia or nightmares).

Side effects of doxycycline hyclate that are different from Cipro include weight loss, skin sensitivity to sunlight, hives, anemia, and vaginal yeast infection.

Cipro may cause serious side effects, including:

• diarrhea
• dizziness
• drowsiness
• headache
• stomach upset
• abdominal pain
• nausea/vomiting
• blurred vision
• nervousness
• anxiety
• agitation
• sleep problems (insomnia or nightmares), and
• rash

Tell your doctor if you experience serious side effects of Cipro including severe dizziness, fainting, fast or pounding heartbeats; sudden pain, snapping or popping sound, bruising, swelling, tenderness, stiffness, or loss of movement in any of your joints; watery or bloody diarrhea; confusion, hallucinations, depression, unusual thoughts or behavior; seizure (convulsions); severe headache, ringing in your ears, pain behind your eyes; pale or yellow skin, dark colored urine, fever, weakness; urinating less than usual or not at all; easy bruising or bleeding; numbness, tingling, or unusual pain anywhere in your body; the first sign of any skin rash, no matter how mild; or severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects of Doxycycline Hyclate include:

• weight loss
• nausea
• vomiting
• diarrhea
• rash
• skin sensitivity to sunlight
• hives
• anemia, and
• vaginal yeast infection

Cipro (ciprofloxacin) is a quinolone antibiotic. Cipro is available as a generic drug and is prescribed to treat infections of the skin, lungs, airways, bones, joints, and urinary tract infections caused by susceptible bacteria.

Doxycycline Hyclate Delayed-Release Tablets is a tetracycline-class antibiotic indicated for rickettsial infections, sexually transmitted infections, respiratory tract infections, specific bacterial infections, ophthalmic infections, anthrax (including inhalational anthrax, post-exposure), alternative treatment for selected infections when penicillin is contraindicated, adjunctive therapy in acute intestinal amebiasis and severe acne, and for prophylaxis of malaria. This medication is available in generic form.

Cipro may also interact with tizanidine, clozapine, cyclosporine, glyburide, methotrexate, metoclopramide, phenytoin, probenecid, ropinirole, theophylline, nonsteroidal anti-inflammatory drugs (NSAIDs) or steroids.

Doxycycline hyclate may interact with anticoagulants, penicillin, antacids (containing aluminum, calcium, or magnesium), bismuth subsalicylate, iron-containing preparations, oral contraceptives, barbiturates, carbamazepine, phenytoin, and methoxyflurane. Tell your doctor all medications and supplements you use. Doxycycline hyclate is not recommended for use during pregnancy. Tetracycline-class drugs can cause fetal harm when administered to a pregnant woman. Doxycycline hyclate passes into breast milk.

• Take Cipro exactly as your healthcare provider tells you to take it.
• Your healthcare provider will tell you how much Cipro to take and when to take it.
• Take Cipro Tablets in the morning and evening at about the same time each day. Swallow the tablet whole. Do not split, crush or chew the tablet. Tell your healthcare provider if you cannot swallow the tablet whole.
• Take Cipro Oral Suspension in the morning and evening at about the same time each day. Shake the Cipro Oral Suspension bottle well each time before use for about 15 seconds to make sure the suspension is mixed well. Close the bottle completely after use.
• Take Cipro XR one time each day at about the same time each day. Swallow the tablet whole. Do not split, crush or chew the tablet. Tell your healthcare provider if you cannot swallow the tablet whole.
• Cipro IV is given to you by intravenous (IV) infusion into your vein, slowly, over 60 minutes, as prescribed by your healthcare provider.
• Cipro can be taken with or without food.
• Cipro should not be taken with dairy products (like milk or yogurt) or calcium-fortified juices alone, but may be taken with a meal that contains these products.
• Drink plenty of fluids while taking Cipro.
• Do not skip any doses of Cipro, or stop taking it, even if you begin to feel better, until you finish your prescribed treatment unless:
  • you have tendon problems. See “What is the most important information I should know about Cipro?”
  • you have nerve problems. See “What is the most important information I should know about Cipro?”
  • you have central nervous system problems. See “What is the most important information I should know about Cipro?”
  • you have a serious allergic reaction. See “What are the possible side effects of Cipro?”
  • your healthcare provider tells you to stop taking Cipro

Taking all of your Cipro doses will help make sure that all of the bacteria are killed. Taking all of your Cipro doses will help lower the chance that the bacteria will become resistant to Cipro. If you become resistant to Cipro, Cipro and other antibacterial medicines may not work for you in the future.

• If you take too much Cipro, call your healthcare provider or get medical help right away.

The usual adult dosage of doxycycline hyclate is 200 mg on the first day of treatment (administered 100 mg every 12 hours) followed by a maintenance dose of 100 mg daily. The pediatric dosage of doxycycline hyclate is based on the child's body weight.