Tumor Necrosis Factor-Alpha (TNF-Alpha) Adenovector

Tumor necrosis factor-alpha (TNF-alpha) adenovector is under investigational use for pancreatic cancer, head and neck cancer, esophageal cancer, and rectal cancer.

Tumor necrosis factor-alpha (TNF-alpha) adenovector is available under the following different brand names: TNFerade.

Dosages of Tumor Necrosis Factor-Alpha (TNF-Alpha) Adenovector:

• Consult your doctor

Dosage Considerations – Should be Given as Follows:

Pancreatic Cancer

• Investigational/Orphan Status
• Intratumoral injections

Other Information

• Intratumoral injection for pancreatic cancer guided by endoscopic ultrasound

Other Indications and Uses

• Investigational: head and neck cancer, esophageal cancer, rectal cancer

Safety and efficacy not established in pediatric patients

Data are limited, and the side effects of tumor necrosis factor-alpha (TNF-alpha) adenovector are unknown.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

• Tumor necrosis factor-alpha (TNF-alpha) adenovector has no listed severe interactions with other drugs.
• Tumor necrosis factor-alpha (TNF-alpha) adenovector has no listed serious interactions with other drugs.
• Tumor necrosis factor-alpha (TNF-alpha) adenovector has no listed moderate interactions with other drugs.
• Tumor necrosis factor-alpha (TNF-alpha) adenovector has no listed mild interactions with other drugs.
   

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

Warnings
 

This medication contains tumor necrosis factor-alpha (TNF-alpha) adenovector. Do not take TNFerade if you are allergic to tumor necrosis factor-alpha (TNF-alpha) adenovector or any ingredients contained in this drug.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

Contraindications

• No information available

Effects of Drug Abuse

• No information available

Short-Term Effects

• See "What Are Side Effects Associated with Using Tumor Necrosis Factor-Alpha (TNF-Alpha) Adenovector?”

Long-Term Effects

• See "What Are Side Effects Associated with Using Tumor Necrosis Factor-Alpha (TNF-Alpha) Adenovector?”

Cautions

• No information available

It is unknown how tumor necrosis factor-alpha (TNF-alpha) adenovector would affect a pregnant woman or her fetus. Avoid pregnancy.

It is unknown if tumor necrosis factor-alpha (TNF-alpha) adenovector is excreted in breast milk. Do not breastfeed while using tumor necrosis factor-alpha (TNF-alpha) adenovector.