Tremfya vs. Skyrizi
Are Tremfya and Skyrizi the Same Thing?
Tremfya (guselkumab) injection and Skyrizi (risankizumab-rzaa) are interleukin-23 blockers used to treat adult patients with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.
Side effects of Tremfya and Skyrizi that are similar include upper respiratory infections, headache, injection site reactions (bruising, redness, fluid leakage, bleeding, infection, inflammation, irritation, pain, itching, swelling, warmth), and tinea infections (ringworm, athlete's foot and jock itch).
Side effects of Tremfya that are different from Skyrizi include joint pain, diarrhea, gastroenteritis (nausea, vomiting, diarrhea, cramps, and fever), and herpes simplex infections.
Side effects of Skyrizi that are different from Tremfya include fatigue.
Both Tremfya and Skyrizi may interact with "live" vaccines.
Tremfya may also interact with and CYP450 substrates.
What Are Possible Side Effects of Tremfya?
Common side effects of Tremfya include:
- upper respiratory infections,
- headache,
- injection site reactions,
- joint pain,
- diarrhea,
- gastroenteritis (nausea, vomiting, diarrhea, cramps, and fever),
- tinea infections (athlete's foot, ringworm, jock itch), and
- herpes simplex infections
What Are Possible Side Effects of Skyrizi?
Common side effects of Skyrizi include
- upper respiratory infections,
- headache,
- fatigue,
- injection site reactions (bruising, redness, fluid leakage, bleeding, infection, inflammation, irritation, pain, itching, swelling, warmth), and
- tinea infections (such as ringworm, athlete's foot and jock itch)
What Is Tremfya?
Tremfya (guselkumab) injection, for subcutaneous use is an interleukin-23 blocker indicated for the treatment of adult patients with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.
What Is Skyrizi?
Skyrizi (risankizumab-rzaa) is an interleukin-23 antagonist indicated for the treatment of moderate-to-severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.
What Drugs Interact With Tremfya?
Tremfya may interact with "live" vaccines and CYP450 substrates. Tell your doctor all medications and supplements you use and all vaccines you recently received. Tell your doctor if you are pregnant or plan to become pregnant before using Tremfya; it is unknown how it would affect a fetus. Human IgG antibodies are known to cross the placental barrier; therefore, Tremfya may be transmitted from the mother to the developing fetus. It is unknown if Tremfya passes into breast milk. Consult your doctor before breastfeeding.
What Drugs Interact With Skyrizi?
Skyrizi may interact with "live" vaccines. Tell your doctor all medications and supplements you use and all vaccines you recently received.
How Should Tremfya be Taken?
The dose of Tremfya is 100 mg administered by subcutaneous injection at Week 0, Week 4 and every 8 weeks thereafter.
How Should Skyrizi be Taken?
The dose of Skyrizi is 150 mg (two 75 mg injections) administered by subcutaneous injection at Week 0, Week 4 and every 12 weeks thereafter.
