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Topamax vs. Trokendi XR

Are Topamax and Trokendi XR the Same Thing?

Topamax (topiramate) and Trokendi XR (topiramate) are anticonvulsants prescribed for preventing epileptic seizures.

Topamax is also used to prevent migraine headaches.

What Are Possible Side Effects of Topamax?

Common side effects of Topamax include:

What Are Possible Side Effects of Trokendi XR?

Common side effects of Trokendi XR include:

A small percent of patients taking Trokendi XR may experience suicidal ideation. If you have thoughts of suicide, tell your doctor immediately.

What is Topamax?

Topamax (topiramate) is an anticonvulsant prescribed for preventing epileptic seizures and migraine headaches. Topamax is available as a generic drug.

What is Trokendi XR?

Trokendi XR (topiramate) Extended-release is a sulfamate-substituted monosaccharide used as initial monotherapy in patients 10 years of age and older with partial onset or primary generalized tonic-clonic seizures and adjunctive therapy in patients 6 years of age and older with partial onset or primary generalized tonic-clonic seizures.

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What Drugs Interact With Topamax?

Topamax may interact with other medicines that can make you sleepy (cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for depression or anxiety), other seizure medications, lithium, hydrochlorothiazide, metformin, atropine, belladonna, benztropine, dimenhydrinate, methscopolamine, scopolamine, bronchodilators, bladder or urinary medications, or glaucoma medications.

What Drugs Interact With Trokendi XR?

Trokendi XR may interact with other seizure medications, other medicines that can make you sleepy (cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for depression or anxiety), metformin, and lithium.

Trokendi XR may also interact with alcohol, oral contraceptives, and carbonic anhydrase inhibitors.

 

How Should Topamax Be Taken?

Topamax usual adult dose is 200mg twice a day. Drug interactions include acetazolamide (Diamox), methazolamide (Neptazane), dichlorphenamide (Daranide), carbamazepine (Tegretol) and phenytoin (Dilantin) and oral contraceptives. There are no adequate studies of Topamax in pregnant women and it is not known if Topamax is secreted in human breast milk. Use during pregnancy is not recommended unless the potential benefit outweighs the potential unknown risk to the fetus. Topamax passes into breast milk and may harm a nursing baby. Consult your doctor before breastfeeding.

How Should Trokendi XR Be Taken?

The recommended dose for Trokendi XR monotherapy in adults and pediatric patients 10 years of age and older is 400 mg orally once daily.