Multaq vs. Tikosyn

• Are Tikosyn and Multaq the Same Thing?
• What Are Possible Side Effects of Multaq?
• What Are Possible Side Effects of Tikosyn?
• What is Multaq?
• What is Tikosyn?
• What Drugs Interact with Multaq?
• What Drugs Interact with Tikosyn?
• How Should Multaq Be Taken?
• How Should Tikosyn Be Taken?

Multaq (dronedarone) and Tikosyn (dofetilide) are antiarrhythmic drugs used to treat atrial fibrillation or atrial flutter, types of abnormal heart rhythms.

Common side effects of Multaq include:

• diarrhea,
• nausea,
• abdominal pain,
• vomiting, and
• weakness.

Common side effects of Tikosyn include:

• headache,
• dizziness,
• nausea,
• diarrhea,
• stomach pain,
• sleep problems (insomnia),
• back pain,
• skin rash, or
• cold symptoms such as stuffy nose, sneezing, or sore throat.

Seek immediate medical attention if you have rare but serious side effects of Tikosyn including:

• chest pain,
• fainting,
• faster or more irregular heartbeat, or
• severe dizziness.

Multaq (dronedarone) is an antiarrythmic drug used to treat atrial fibrillation or atrial flutter, types of abnormal heart rhythms.

Tikosyn (sotalol) is an antiarrhythmic agent used for treating ventricular arrhythmias.

Multaq may interact with cyclosporine, dexamethasone, medications for treating tuberculosis, cyclosporine, sirolimus, tacrolimus, St. John's wort, theophylline, antibiotics, antifungals, antidepressants, anti-malaria medications, barbiturates, beta-blockers, cholesterol-lowering medicines, heart or blood pressure medications, heart rhythm medicines, medicines to prevent blood clots, medicines to prevent or treat nausea and vomiting, medicines to treat HIV/AIDS or hepatitis C, medicines to treat psychiatric disorders, migraine headache medicines, narcotics, seizure medications, and other drugs. Tell your doctor all medications and supplements you use. Do not use Multaq if you are pregnant.

Tikosyn may interact with diuretics (water pills), HIV/AIDS medicine, drugs that can affect heart rhythm, narcotics, antibiotics, antidepressants, medicines to treat psychiatric disorders, or heart rhythm medicine. Tell your doctor all medications you are taking.

The recommended dosage of Multaq is 400 mg twice daily in adults. Multaq should be taken as one tablet with the morning meal and one tablet with the evening meal.

The usual recommended dose of Tikosyn is 500 mcg twice daily. When starting, restarting, or increasing the dose, you will need to stay in the hospital for at least 3 days for monitoring.