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Definition of Dermatan sulfate
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
Dermatan sulfate: An glycosaminoglycan (formerly called a mucopolysaccharide) found mostly in skin but also in blood vessels, the heart valves, tendons, and the lungs. Dermatan sulfate accumulates abnormally in several of the mucopolysaccharidosis disorders.