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Definition of de Musset sign
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
de Musset sign: Rhythmic nodding or bobbing of the head in synchrony with the heart beat, a sign of aortic insufficiency --incompetence of the aortic valve with aortic regurgitation. The causes include syphilitic aortitis, rheumatic fever, and aortic aneurysm. Named after the French Romantic poet and playwright Alfred de Musset (1810-1857).