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Definition of Neuroleptic
Medically reviewed by Min Clinic Staff | Updated: January 2026
Neuroleptic: A term that refers to the effects of antipsychotic drugs on a patient, especially on his or her cognition and behavior.
Neuroleptic drugs may produce a state of apathy, lack of initiative and limited range of emotion. In psychotic patients, neuroleptic drugs cause a reduction in confusion and agitation and tend to normalize psychomotor activity.
The term comes from the Greek "lepsis" meaning a taking hold.