Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of Vesicle

Medically reviewed by Min Clinic Staff | Updated: January 2026

Vesicle: In dermatology, a vesicle is a small blister, as on the skin. Vesicles also occur on the mucous membranes, such as the buccal mucosa (the lining of the mouth). Vesicles are less than 0.5 centimeters in diameter.

In anatomy, a vesicle is any small pouch. For example, the seminal vesicles are a pair of pouch-like structures about five cm (2 inches) long located behind the bladder and above the prostate gland that contribute fluid to the ejaculate.

The word vesicle comes from the Latin diminutive vesiculum meaning a small bag or bladder.