Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Southern tick-associated rash illness
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
Southern tick-associated rash illness: A disease characterized by a rash like that in Lyme disease, recognized in the southeastern and south-central US, associated with the bite of the lone star tick, Amblyomma americanum. The tick transmits the agent of the disease, a spirochete named Borrelia lonestari. The rash is red and expands with central clearing (the rash of erythema migrans). Treatment is with antibiotics.
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