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Definition of Seroconversion
Medically reviewed by Min Clinic Staff | Updated: January 2026
Seroconversion: The development of detectable antibodies in the blood that are directed against an infectious agent. Antibodies do not usually develop until some time after the initial exposure to the agent. Following seroconversion, a person tests positive for the antibody when given tests that are based on the presence of antibodies, such as ELISA.