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Definition of Hemolytic anemia
Medically reviewed by Min Clinic Staff | Updated: January 2026
Hemolytic anemia: Anemia due to the destruction, rather than underproduction, of red blood cells. Hemolytic anemia can result from a medication reaction, from the immune system attacking the red blood cells (autoimmune hemolytic anemia), from destruction of blood cells passing through diseased heart valves, and other causes.