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Definition of Naloxone

Medically reviewed by Min Clinic Staff | Updated: January 2026

Naloxone: A drug that antagonizes morphine and other opiates. Naloxone is a pure opiate antagonist and prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Sold under the brand name of Narcan and in combination with buprenorphine as Suboxone.