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Visipaque: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Visipaque - General Information

Visipaque is commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.

 

Pharmacology of Visipaque

Visipaque is a contrast agent commonly used during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents. It is an iso-osmolar contrast agent, with an osmolality of 290 mOsm/kg H20, the same as blood.

 

Additional information about Visipaque

Visipaque Indication: Used as a contrast agent during coronary angiography. Mechanism Of Action: Organic iodine compounds attenuate x-rays as they pass through the body, thereby allowing the body structures containing iodine to be delineated in contrast to those structures that do not contain iodine. The degree of opacity produced by these compounds is directly proportional to the total amount (concentration and volume) of the iodinated contrast agent in the path of the x-rays. After intravascular administration, iodixanol makes opaque those internal structures in its path of flow, allowing their visualization until significant hemodilution and elimination occur. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Iodixanol Synonyms: Indixanol; Iodixanolum Drug Category: Contrast Media Drug Type: Small Molecule; Approved Other Brand Names containing Iodixanol: Visipaque; Visipaque 270; Visipaque 320; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: Negligible Biotransformation: Excreted unchanged Half Life: 2.1 hours. In patients with significantly impaired renal function (mean creatinine clearance rate, 9.91 [± 3.58] mL per minute), the plasma half-life is increased to 23 hours. Dosage Forms of Visipaque: Solution Intra-arterial Chemical IUPAC Name: 5-[acetyl-[3-[acetyl-[3,5-bis(2,3-dihydroxypropylcarbamoyl)-2,4,6-triiodophenyl]amino]-2-hydroxypropyl]amino]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide Chemical Formula: C35H44I6N6O15 Iodixanol on Wikipedia: https://en.wikipedia.org/wiki/Iodixanol Organisms Affected: Humans and other mammals