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Megatope (IsoTex Diagnostics): Full Drug Profile

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Megatope (IsoTex Diagnostics) - General Information

A diagnostic radiopharmaceutical containing iodinated I 131 albumin for intravenous imaging. Following intravenous injection, radioiodinated albumin human is uniformly distributed throughout the intravascular pool within 10 minutes; extravascular distribution takes place more slowly (2 days). Megatope is indicated for use in determinations of total blood and plasma volumes, cardiac output, cardiac and pulmonary blood volumes and circulation times

 

Pharmacology of Megatope (IsoTex Diagnostics)

Regulates the colloidal osmotic pressure of blood. It is used to increase the circulating plasma volume, thereby reducing hemoconcentrtion and blood viscosity. Also used as a transport protein that binds naturally occurring, therapeutic and toxic materials in circulation.

 

Additional information about Megatope (IsoTex Diagnostics)

Megatope (IsoTex Diagnostics) Indication

For determination of total blood and plasma volumes

Mechanism Of Action
Serum albumin acts as a high molecular weight, very soluble osmolyte
Generic Name
Serum albumin iodonated
Synonyms
Serum albumin precursor
Drug Category
Imaging Agents
Drug Type
Biotech; Approved
Other Brand Names containing Serum albumin iodonated
Megatope (IsoTex Diagnostics);
Chemical IUPAC Name
Human serum albumin
Chemical Formula
C2936H4624N786O889S41
Organisms Affected
Humans and other mammals