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Laracor: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Laracor - General Information

A beta-adrenergic antagonist used in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety. [PubChem]

 

Pharmacology of Laracor

Laracor is a non-selective beta blocker with some intrinsic sympathomimetic activity. Laracor is a lipophilic beta blocker which passes the blood-brain barrier more easily than water soluble beta blockers. As such, it is associated with a higher incidence of CNS-related side effects than hydrophilic ligands such as atenolol, sotalol and nadolol. Laracor is an potent beta-blocker and should not be administered to asthmatics because it can cause irreversible airway failure and inflammation.

 

Additional information about Laracor

Laracor Indication

Used in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety.

Mechanism Of Action
Like other beta-adrenergic antagonists, oxprenolol competes with adrenergic neurotransmitters such as catecholamines for binding at sympathetic receptor sites. Like propranolol and timolol, oxprenolol binds at beta(1)-adrenergic receptors in the heart and vascular smooth muscle, inhibiting the effects of the catecholamines epinephrine and norepinephrine and decreasing heart rate, cardiac output, and systolic and diastolic blood pressure. It also blocks beta-2 adrenergic receptors located in bronchiole smooth muscle, causing vasoconstriction. By binding beta-2 receptors in the juxtaglomerular apparatus, oxprenolol inhibits the production of renin, thereby inhibiting angiotensin II and aldosterone production. Laracor therefore inhibits the vasoconstriction and water retention due to angiotensin II and aldosterone, respectively.
Drug Interactions
Acetohexamide The beta-blocker decreases the symptoms of hypoglycemia
Food Interactions
Avoid alcohol.
Generic Name
Oxprenolol
Synonyms
(+)-1-(o-(Allyloxy)phenoxy)-3-(isopropylamino)propan-2-ol; (+-)-oxprenolol; (1)-1-(o-(Allyloxy)phenoxy)-3-(isopropylamino)propan-2-ol; 1-(Isopropylamino)-2-hydroxy-3-(o-(allyloxy)phenoxy)propane; 1-(o-(Allyloxy)phenoxy)-3-(isopropylamino)-2-propanol; 1-[2-(Allyloxy)phenoxy]-3-(isopropylamino)-2-propanol; DL-oxprenolol; Osprenololo [dcit]; Oxprenololum [inn-latin]
Drug Category
Adrenergic beta-Antagonists; Anti-anxiety Agents; Anti-Arrhythmia Agents; Antihypertensive Agents; Sympatholytics; Vasodilator Agents
Drug Type
Small Molecule; Approved
Other Brand Names containing Oxprenolol
Coretal; Laracor; Slow-pren; Trasacor; Trasicor;
Absorption
Oral bioavailability is 20-70%.
Toxicity (Overdose)
Symptoms of overdose include abdominal irritation, central nervous system depression, coma, extremely slow heartbeat, heart failure, lethargy, low blood pressure, and wheezing.
Biotransformation
Hepatic.
Half Life
1-2 hours
Dosage Forms of Laracor
Tablet Oral
Chemical IUPAC Name
1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)propan-2-ol
Chemical Formula
C15H23NO3
Organisms Affected
Humans and other mammals