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gepirone (Travivo): Dosing and Uses

 

Classes: Antidepressants, Other

Medically reviewed by Min Clinic Staff | Updated: January 2026

Dosing and uses of Travivo (gepirone)

 

Major Depressive Disorder

Pending FDA approval for treatment of major depressive disorder

 

Pharmacology of Travivo (gepirone)

Mechanism of action

Serotonin (5HT)-1a agonist; activation of 5HT-1a leads to glutamate inhibition; without glutamate activation of GABA interneurons, there is no inhibitory control over dopamine release, thereby, increasing dopamine release