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solithromycin (Solithera)

 

Classes: Ketolides

Dosing and uses of Solithera (solithromycin)

 

Pneumonia

Pending FDA approval for moderate-to-severe community-acquired bacterial pneumonia

 

Pharmacology of Solithera (solithromycin)

Mechanism of action

Fluoroketolide which binds to 3 sites on the 50S subunit of the bacterial ribosome compared with older macrolides which bind to 1 site on the ribosome