Dosing and uses of Solithera (solithromycin)
Pneumonia
Pending FDA approval for moderate-to-severe community-acquired bacterial pneumonia
Pharmacology of Solithera (solithromycin)
Mechanism of action
Fluoroketolide which binds to 3 sites on the 50S subunit of the bacterial ribosome compared with older macrolides which bind to 1 site on the ribosome