multivitamins, vision (Ocuvite Adult 50+ Age-adjusted Formula, Ocuvite Eye Vitamins and Mineral Supplements, Ocuvite Lutein Eye Vitamins, PreserVision Eye Vitamin AREDS 2 Formula Soft Gels, PreserVision Eye Vitamin AREDS Formula Soft Gels, PreserVision Eye Vitamin AREDS Formula Tablets, PreserVision Eye Vitamin Lutein Formula Soft Gels, ICAPS Eye Vitamin AREDS Formula, ICAPS Eye Vitamin Lutein and Omega-3 Vitamin, ICAPS Eye Vitamin Lutein and Zeaxanthin Formula, ICAPS Eye Vitamin Multivitamin Formula)
Classes: Vitamins, Combos
- Dosing and uses of Ocuvite Eye Vitamins & Mineral Supplements, PreserVision Eye Vitamin AREDS (multivitamins, vision)
- Ocuvite Eye Vitamins & Mineral Supplements, PreserVision Eye Vitamin AREDS (multivitamins, vision) adverse (side) effects
- Warnings
- Pregnancy
- Pharmacology of Ocuvite Eye Vitamins & Mineral Supplements, PreserVision Eye Vitamin AREDS (multivitamins, vision)
Dosing and uses of Ocuvite Eye Vitamins and Mineral Supplements, PreserVision Eye Vitamin AREDS (multivitamins, vision)
Adult dosage forms and strengths
Large number of products available; consult each product labeling
Age-Related Macular Degeneration
In a National Eye Institute’s age-related eye study (AREDS results showed a reduction in risk of 25% for developing advanced AMD and a 19% reduction in the risk of vision loss among moderate to advanced AMD patients
PreserVision Eye Vitamin AREDS 2 Formula Soft Gels
- [capsule]: zinc 17.4 mg; vitamin C 113 mg; vitamin E 100 IU; omega-3 250 mg; lutein 2.5 mg; zeaxanthin 2 mg (replaces beta-carotene)
- 1 capsule PO twice daily with morning and evening meals
PreserVision Eye Vitamin AREDS Formula Soft Gels
- [capsule]: zinc 34.8 mg; vitamin A 14, 320 IU; vitamin C 226 mg; vitamin E 200 IU; copper 0.8 mg
- 1 capsule PO twice daily with morning and evening meals
PreserVision Eye Vitamin AREDS Formula Tablets
- [tablet]: zinc 17.4 mg; vitamin A 7,160 IU; vitamin C 113 mg; vitamin E 100 IU; copper 0.4 mg
- 2 tablets PO twice daily with morning and evening meals
PreserVision Eye Vitamin Lutein Formula Soft Gels
- [capsule]: zinc 34.8 mg; vitamins C 226 mg & E 200 IU; copper 0.8 mg; lutein 5 mg
- 1 capsule PO twice daily with morning and evening meals
ICAPS Eye Vitamin AREDS Formula
- [soft-gel cap]: zinc 17.4 mg; vitamin A 7,160 IU; vitamin C 113 mg; vitamin E 100 IU; copper 0.4 mg
- 2 capsules PO twice daily with morning and evening meals
Ocular Vitamin Supplementation
Ocuvite Adult 50+ Age-adjusted Formula
- [capsule]: zinc 9 mg; vitamin C 150 mg; vitamin E 30 IU; copper 1 mg; lutein 6 mg; omega-3 150 mg
- 1 capsule qDay, in morning taken with food
- Do not exceed the dose indicated without seeking medical advice
Ocuvite Eye Vitamins & Mineral Supplements
- [tablet]: zinc 40 mg; vitamin A 1,000 IU; vitamin C 200 mg; vitamin E 60 IU; copper 2 mg; selenium 55 mcg; lutein 2 mg
- 1 tablet qDay or twice daily as directed by physician
Ocuvite Lutein Eye Vitamins
- [capsule] zinc 15 mg; vitamin C 60 mg; vitamin E 30 IU; copper 2 mg; lutein 6 mg
- 1 capsule qDay or twice daily as directed by physician
ICAPS Eye Vitamin Lutein & Omega-3 Vitamin
- [soft-gel cap]: vitamin A 600 mcg; vitamin C 45 mg; vitamin E 10 IU; thiamine 1.2 mg; riboflavin 1.3 mg; niacin 16 mg; vitamin B6 1.3 mg; folic acid 250 mcg; vitamin B12 2.4 mcg; calcium 1 mg; zinc 7 mg; selenium 34 mcg; copper 0.9 mg; manganese 2.3 mg; lutein 10 mg; zeaxanthin 2 mg; omega-3 fatty acids 280 mg
- 1 tablet PO qDay with a meal
ICAPS Eye Vitamin Lutein & Zeaxanthin Formula
- [tablet]: vitamin A 3,300 IU; vitamin C 200 mg; vitamin E (dt-alpha tocopheryl acetate) 75 IU; riboflavin 5 mg; zinc 30 mg; copper 4 mg; manganese 5 mg; selenium 20 mcg; lutein/zeaxanthin 2 mg; calcium 20 mg
- 2 tablets PO qDay with a meal
ICAPS Eye Vitamin Multivitamin Formula
- [tablet]: vitamin C 128 mg; vitamin D 100 IU; vitamin E 107.5 IU; vitamin K 7.25 mcg; thiamin 0.375 mg; riboflavin 2.5 mg; niacin 2.5 mg; vitamin B6 0.5 mg; folic acid 100 mcg; vitamin B12 1.5 mcg; biotin 7.5 mcg; pantothenic acid 2.5 mg; calcium 82.5 mg; phosphorus 35 mg; iodine 37.5 mcg; magnesium 25 mg; zinc 21.15 mg; selenium 10 mcg; copper 0.9 mg; manganese 0.5 mg; chromium 30 mcg; molybdenum 18.75 mcg; potassium 20 mg; lutein 1.66 mg; zeaxanthin 0.83 mg; lycopene 0.075 mg
- 2 tablets PO twice daily with meals
Pediatric dosage forms and strengths
Safety and efficacy not established
Ocuvite Eye Vitamins and Mineral Supplements, PreserVision Eye Vitamin AREDS (multivitamins, vision) adverse (side) effects
Frequency not defined
Nausea
GI distress
Warnings
Contraindications
Hypersensitivity
Cautions
Avoid high doses of beta-carotene in individuals who smoke; associated with increased risk of lung cancer in males and tobacco-related cancers in women
Pregnancy and lactation
Pregnancy category: C
Lactation: distributed in breast milk, caution advised
These vitamins are not intended for pregnancy or breastfeeding
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Ocuvite Eye Vitamins and Mineral Supplements, PreserVision Eye Vitamin AREDS (multivitamins, vision)
Mechanism of action
Antioxidant vitamins and minerals
- Strategies to prevent the conversion from dry AMD to wet AMD include high-dose consumption of the antioxidant vitamins, C, E, and beta-carotene, plus the minerals zinc and copper
- Over a 10-year period, researchers conducting a trial sponsored by the Age-related Eye Disease Study (AREDS) Research Group observed a significant reduction in the development of wet AMD in at-risk individuals who used the Ocuvite PreserVision preparation containing vitamins A, C, and E as well as zinc and copper compared with those who took antioxidants alone, zinc plus copper, or placebo
- Lutein, omega-3 fatty acids, and zeaxanthin may also provide risk reduction for AMD
- Lutein, a carotenoid found in dark leafy green vegetables, is currently being evaluated in the AREDS-2 trial