folic acid/cyanocobalamin/pyridoxine (Foltx, folic acid/vitamin B12/vitamin B6, Folbic)
Classes: Vitamins, Combos
- Dosing and uses of Foltx, folic acid/vitamin B12/vitamin B6 (folic-acid-cyanocobalamin-pyridoxine)
- Foltx, folic acid/vitamin B12/vitamin B6 (folic-acid-cyanocobalamin-pyridoxine) adverse (side) effects
- Warnings
- Pregnancy
- Nutrition
- Pharmacology of Foltx, folic acid/vitamin B12/vitamin B6 (folic-acid-cyanocobalamin-pyridoxine)
Dosing and uses of Foltx, folic acid/vitamin B12/vitamin B6 (folic-acid-cyanocobalamin-pyridoxine)
Adult dosage forms and strengths
folic acid/cyanocobalamin/pyridoxine
tablet
- 0.4mg/250mg/25mg
- 0.8mg/100mcg/50mg
- 0.8mg/1000mcg/50mg
- 0.8mg/115mcg/10mg
- 0.8mg/250mcg/25mg
- 0.8mg/400mcg/25mg
- 2.2mg/500mcg/25mg
- 2.2mg/1000mcg/25mg
- 2.2mg/1300mcg/25mg
- 2.5mg/2000mcg/25mg
- 2.5mg/1000mcg/25mg
Daily Dietary Supplement
1 tab PO qDay
Pediatric dosage forms and strengths
Safety & efficacy not established
Foltx, folic acid/vitamin B12/vitamin B6 (folic-acid-cyanocobalamin-pyridoxine) adverse (side) effects
Frequency not defined
Allergic reactions
Bronchospasm
Flushing
Malaise
Erythema
Rash
Paresthesias
Somnolence
Unsteady gait
Diarrhea
Nausea
Pruritus
Urticaria
Altered sleep patterns
Irritability
Peripheral vascular thrombosis
Polycythemia
Warnings
Contraindications
Hypersensitivity to any component
Pregnancy and lactation
Pregnancy category: See individual agents
Lactation: Safe
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Nutrition
See individual monographs
Pharmacology of Foltx, folic acid/vitamin B12/vitamin B6 (folic-acid-cyanocobalamin-pyridoxine)
Mechanism of action
Folic acid: Plays a role in the formation of coenzymes involved in purine and pyrimidine synthesis as well as other metabolic systems; required for nucleoprotein synthesis and maintenance of erythropoiesis; enhances metabolism of formic acid, the toxic metabolite of methanol, to nontoxic metabolites
Cyanocobalamin: Plays a role in cell replication and hematopoiesis; coenzyme in protein synthesis as well as fat and carbohydrate metabolism
Pyridoxine: Plays a role in carbohydrate, protein, and fat metabolism; aids in the release of liver and muscle stored glycogen and the synthesis of GABA