Dosing and uses of Exelderm (sulconazole)
Adult dosage forms and strengths
cream/topical solution
- 1%
Tinea Infection
Tinea corporis, cruris, versicolor: apply cream or solution qHS or BID x 3 weeks
Tinea pedis: apply cream qHS or BID x 3-4 weeks
Other Indications & Uses
Cruris, corporis, versicolor
Pediatric dosage forms and strengths
Safety & efficacy not established
Exelderm (sulconazole) adverse (side) effects
1-10%
Pruritus
Erythema
Burning
Irritation
Stinging/tingling
Warnings
Contraindications
Hypersensitivity
Not for ophthalmic or intravaginal use
Cautions
Hypersensivity to other azole antifungals (eg, miconazole, ketoconazole, itraconazole)
Pregnancy and lactation
Pregnancy category: C
Lactation: not known whether topical preparations get into breast milk; use caution
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Exelderm (sulconazole)
Absorption: 8.7-11.3%
Excretion
Urine: 6.7%
Feces: 2%
Mechanism of action
Antifungal ointment, interferes with cell membrane sterol biosynthesis
