polymyxin B/bacitracin topical (Double Antibiotic Ointment, Polysporin)
Classes: Antibacterials, Topical
Dosing and uses of Double Antibiotic Ointment, Polysporin (polymyxin B/bacitracin topical)
Adult dosage forms and strengths
polymyxin B/bacitracin topicaL
topical ointment, cream
- (10,000unit/500unit)/g
Treatment/Prophylaxis Superficial Skin Infection
Apply topically qD-TId
Other Information
For gram-pos & gram-neg infections
Good broad spectrum coverage
Does not cause allergic contact dermatitis like neosporin or other neomycin containing topical antibiotic preparations
Pediatric dosage forms and strengths
polymyxin B/bacitracin topicaL
topical ointment, cream
- (10,000unit/500unit)/g
Treatment/Prevention Superficial Skin Infection
Apply Topically qD-TId
Other Information
For gram-pos & gram-neg infections
Good broad spectrum coverage
Does not cause allergic contact dermatitis like neosporin or other neomycin containing topical antibiotic preparations
Double Antibiotic Ointment, Polysporin (polymyxin B/bacitracin topical) adverse (side) effects
<1%
Allergic contact dermatitis
Warnings
Contraindications
Hypersensitivity
Not for ophthalmic use or over large areas of body
Pregnancy and lactation
Pregnancy category: C
Lactation: unknown if distributed in breast milk
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Double Antibiotic Ointment, Polysporin (polymyxin B/bacitracin topical)
See individual monograph for further details:
Bacitracin
Mechanism of action
AntibacteriaL
