polymyxin B/bacitracin topical (Double Antibiotic Ointment, Polysporin): Dosing and Uses

Dosing and uses of Double Antibiotic Ointment, Polysporin (polymyxin B/bacitracin topical)

• Adult
• Pediatric

Adult dosage forms and strengths

polymyxin B/bacitracin topicaL

topical ointment, cream

• (10,000unit/500unit)/g

Treatment/Prophylaxis Superficial Skin Infection

Apply topically qD-TId

Other Information

For gram-pos & gram-neg infections

Good broad spectrum coverage

Does not cause allergic contact dermatitis like neosporin or other neomycin containing topical antibiotic preparations

Pediatric dosage forms and strengths

polymyxin B/bacitracin topicaL

topical ointment, cream

• (10,000unit/500unit)/g

Treatment/Prevention Superficial Skin Infection

Apply Topically qD-TId

Other Information

For gram-pos & gram-neg infections

Good broad spectrum coverage

Does not cause allergic contact dermatitis like neosporin or other neomycin containing topical antibiotic preparations

Double Antibiotic Ointment, Polysporin (polymyxin B/bacitracin topical) adverse (side) effects

<1%

Allergic contact dermatitis

Warnings

Contraindications

Hypersensitivity

Not for ophthalmic use or over large areas of body

Pregnancy and lactation

Pregnancy category: C

Lactation: unknown if distributed in breast milk

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

Pharmacology of Double Antibiotic Ointment, Polysporin (polymyxin B/bacitracin topical)

See individual monograph for further details:

Bacitracin

Mechanism of action

AntibacteriaL