Suggested dosing of Cynara scolymus, cynarin (artichoke)
500 mg/d dry extract, no more than 6 g/d
Dyspepsia
320-640 mg artichoke leaf extract PO TId
Hyperlipidemia
1800-1920 mg PO qD div BID-TID (Valverde Artischocke, Novartis Consumer Health)
Suggested uses of Cynara scolymus, cynarin (artichoke)
Appetite loss, liver & gall bladder problems
Efficacy: possibly effective for dyspepsia and hyperlipidemia
Cynara scolymus, cynarin (artichoke) adverse (side) effects
None reported
Warnings
Contraindications
Bile duct blockage
Cautions
Gallstones
Possibility of allergic reactions on frequent contact
Pregnancy and lactation
Pregnancy category: N/A
Lactation: N/A
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Cynara scolymus, cynarin (artichoke)
Metabolism: N/A
Excretion: N/A
Mechanism of action
Cholagogue, contains an active ingredient-Cynarin
