Dosing and uses of Cortisporin Cream, Cortisporin Ointment (neomycin topical)
Steroid Responsive Dermatoses with Infection
Apply cream/ointment BID-QID x up to 7d
Other Indications & Uses
Treatment of corticosteroid-responsive dermatoses with secondary infection
Prophylaxis of skin infection in minor injury
Pediatric dosage forms and strengths
Safety and efficacy not established
Cortisporin Cream, Cortisporin Ointment (neomycin topical) adverse (side) effects
Frequency not defined
Skin sensitization
Burning
Itching
Irritation
Dryness
Folliculitis
Hypertrichosis
Acneiform eruptions
Hypopigmentation
Perioral dermatitis
Allergic contact dermatitis
Maceration of the skin
Secondary infection
Skin atrophy
Striae
Miliaria
Warnings
Contraindications
Hypersensitivity
Cautions
For external use only
Pregnancy and lactation
Pregnancy category: C
Lactation: use with caution
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Cortisporin Cream, Cortisporin Ointment (neomycin topical)
Corticosteroid potency: Mild to medium
Mechanism of action
Neomycin and polymyxin: Active against: Staphylococcus aureus, Escherichia coli, Haemophilus influenzae, Klebsiella-Enterobacter species, Neisseria species, and Pseudomonas aeruginosa
Hydrocortisone: Antipruritic/anti-inflammatory action
