Cozaar vs. Hyzaar

• Are Hyzaar and Cozaar the Same Thing?
• What Are Possible Side Effects of Cozaar?
• What Are Possible Side Effects of Hyzaar?
• What is Cozaar?
• What is Hyzaar?
• What Drugs Interact with Cozaar?
• What Drugs Interact with Hyzaar?
• How Should Cozaar Be Taken?
• How Should Hyzaar Be Taken?

Cozaar (losartan) and Hyzaar (losartan potassium-hydrochlorothiazide) are prescribed for the treatment of hypertension.

Hyzaar is also used to lower the risk of stroke in certain people with heart disease.

Cozaar and Hyzaar both contain an angiotensin receptor blocker (ARB), and Hyzaar is a combination medication that also contains a thiazide diuretic (water pill).

Common side effects of Cozaar include:

• diarrhea
• stomach pain
• muscle cramps
• leg or back pain
• dizziness
• headache
• sleep problems (insomnia)
• tiredness, and
• cold or flu symptoms such as stuffy nose, sneezing, sore throat, fever, and cough

Tell your doctor if you experience serious side effects of Cozaar including pain or burning when you urinate; pale skin, lightheadedness, shortness of breath, rapid heart rate, trouble concentrating; wheezing, chest pain; drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting; swelling, weight gain, urinating less than usual or not at all; or high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling).

Common side effects of Hyzaar include:

• dizziness or lightheadedness as your body adjusts to the medication,
• stomach pain,
• back pain,
• tired feeling,
• skin rash,
• runny or stuffy nose,
• sore throat, or
• dry cough.

Cozaar (losartan) is an oral angiotensin receptor blocker (ARB) prescribed for the treatment of hypertension.

Hyzaar (losartan potassium-hydrochlorothiazide) is a combination of an angiotensin II receptor antagonist and a thiazide diuretic (water pill) used to treat high blood pressure (hypertension). Hyzaar is also used to lower the risk of stroke in certain people with heart disease.

Cozaar may interact with diuretics (water pills), other blood pressure medications, lithium, celecoxib, or aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs).

Hyzaar may interact with other blood pressure medications, lithium, celecoxib, diuretics (water pills), or aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs).

Hyzaar may also interact with steroids, cholestyramine or colestipol, insulin or oral diabetes medications, rifampin, barbiturates, muscle relaxers, or narcotic pain medications.

Dosing preparations of Cozaar are 25, 50, and 100 mg tablets. Drug interactions with Cozaar may occur with inhibitors of cytochrome P450, potassium- sparing diuretics, and nonsteroidal anti-inflammatory drugs (NSAIDs). Cozaar should not be used during pregnancy, and it is not known whether it is excreted in breast milk.

Dose of Hyzaar is individualized, and ranges from 50/12.5 (losartan/ hydrochlorothiazide) to 100/25 (losartan/ hydrochlorothiazide). Hyzaar may interact with other blood pressure medications, steroids, lithium, celecoxib, cholestyramine or colestipol, insulin or oral diabetes medications, rifampin, barbiturates, other diuretics, aspirin, NSAIDs (nonsteroidal anti-inflammatory drugs), muscle relaxers, or narcotics. Tell your doctor all medications you use. Hyzaar is not recommended for use during pregnancy due to the risk for harm to a fetus. It is unknown if losartan passes into breast milk. Hydrochlorothiazide passes into breast milk, but is unlikely to harm a nursing infant. Consult your doctor before breastfeeding.