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Xcopri vs. Keppra

Are Xcopri and Keppra the Same Thing?

Xcopri (cenobamate tablets) and Keppra (levetiracetam) are antiepileptic drugs (AEDs) used to treat partial-onset seizures in adults.

Keppra is also used to treat partial-onset seizures in children 1 month of age and older.

Side effects of Xcopri and Keppra that are similar include drowsiness, dizziness, and fatigue/tiredness.

Side effects of Xcopri that are different from Keppra include double vision and headache.

Side effects of Keppra that are different from Xcopri include weakness, infection, loss of appetite, and stuffy nose.

Both Xcopri and Keppra may interact with other antiepileptic drugs (AEDs) and oral contraceptives.

Xcopri may also interact with CYP2B6 and CYP3A substrates, CYP2C19 substrates, other drugs that shorten the QT interval, alcohol, and other CNS depressants.

Keppra may also interact with digoxin, warfarin, and probenecid.

What Are Possible Side Effects of Xcopri?

Common side effects of Xcopri include:

  • drowsiness,
  • dizziness,
  • fatigue,
  • double vision, and
  • headache

What Are Possible Side Effects of Keppra?

Common side effects of Keppra include:

  • drowsiness,
  • weakness,
  • infection,
  • loss of appetite,
  • stuffy nose,
  • tiredness, and
  • dizziness.

Side effects of Keppra in children include

  • sleepiness,
  • accidental injury,
  • hostility, nervousness, and
  • weakness.

What Is Xcopri?

Xcopri (cenobamate tablets) is an antiepileptic drug (AED) used to treat partial-onset seizures in adult patients.

What Is Keppra?

Keppra (levetiracetam) is an anti-epileptic drug (AED) (antoconvulsant) often used in conjunction with other drugs to treat types of seizures in people with epilepsy.

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What Drugs Interact With Xcopri?

Xcopri may interact with other medicines such as:

  • antiepileptic drugs (AEDs),
  • CYP2B6 and CYP3A substrates,
  • CYP2C19 substrates,
  • oral contraceptives,
  • other drugs that shorten the QT interval,
  • alcohol, and
  • other CNS depressants

Tell your doctor all medications and supplements you use and all vaccines you recently received.

What Drugs Interact With Keppra?

Keppra may interact with alcohol.

Tell your doctor all medications and supplements you use.

 

How Should Xcopri Be Taken?

The recommended initial dosage of Xcopri is 12.5 mg once daily, adjusted to the recommended maintenance dosage of 200 mg once daily.

How Should Keppra Be Taken?

Keppra (levetiracetam) is available in pills in the following dosages and colors: 250 mg (blue), 500 mg (yellow), 750 mg (orange), and 1,000 mg (white). Keppra (levetiracetam) is also available as a clear, colorless grape-flavored liquid at a concentration of 100 mg/mL. Drug interactions include phenytoin, valproate, oral contraceptives, digoxin, warfarin, and probenecid. Keppra (levetiracetam) should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Keppra (levetiracetam) is excreted in breast milk. Women must talk to their doctors to decide whether to discontinue nursing or the drug.