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Vumerity vs. Tecfidera

Are Vumerity and Tecfidera the Same Thing?

Vumerity (diroximel fumarate) and Tecfidera (dimethyl fumarate) are immunomodulators used to treat relapsing forms of multiple sclerosis (MS).

Side effects of Vumerity and Tecfidera that are similar include flushing, abdominal pain, diarrhea, nausea, vomiting, itching, rash, redness, and indigestion/heartburn.

Side effects of Vumerity that are different from Tecfidera include albumin in the urine.

Vumerity may interact with dimethyl fumarate.

Tecfidera may interact with other drugs.

What Are Possible Side Effects of Vumerity?

Common side effects of Vumerity include:

  • flushing,
  • abdominal pain,
  • diarrhea,
  • nausea,
  • vomiting,
  • itching,
  • rash,
  • albumin in the urine,
  • redness, and
  • indigestion/heartburn

What Are Possible Side Effects of Tecfidera?

Common side effects of Tecfidera include:

  • flushing,
  • abdominal pain,
  • diarrhea,
  • nausea,
  • vomiting,
  • rash,
  • itching,
  • redness, and
  • indigestion.

What Is Vumerity?

Vumerity (diroximel fumarate) is an immunomodulator indicated for the treatment of relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

What Is Tecfidera?

Tecfidera (dimethyl fumarate) is a fumaric acid ester used to treat relapsing forms of multiple sclerosis (MS).

 

What Drugs Interact With Vumerity?

Vumerity may interact with other medicines such as:

  • dimethyl fumarate

Tell your doctor all medications and supplements you use.

What Drugs Interact With Tecfidera?

Tecfidera may interact with other drugs. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to be become pregnant before using Tecfidera; it is unknown how it would affect a fetus. There is a pregnancy registry that monitors pregnancy outcomes in women exposed to Tecfidera during pregnancy and you may be encouraged to enroll. It is unknown if Tecfidera passes into breast milk. Consult your doctor before breastfeeding.

 

How Should Vumerity Be Taken?

The starting dose of Vumerity is 231 mg twice a day, orally, for 7 days. The maintenance dose of Vumerity after 7 days is 462 mg (administered as two 231 mg capsules) twice a day, orally.

How Should Tecfidera Be Taken?

The starting dose of Tecfidera is 120 mg twice daily for seven days by mouth. After seven days, maintenance doses of Tecfidera are 240 mg taken twice daily by mouth.