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Rybelsus vs. Ozempic

Are Rybelsus and Ozempic the Same Thing?

Rybelsus (semaglutide) and Ozempic (semaglutide) Injection glucagon-like peptide-1 (GLP-1) receptor agonists used as adjuncts to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Side effects of Rybelsus and Ozempic that are similar include nausea, abdominal pain, diarrhea, vomiting, and constipation.

Side effects of Rybelsus that are different from Ozempic include decreased appetite.

Both Rybelsus and Ozempic may interact with insulin secretagogues or insulin, and other oral medications taken at the same time.

What Are Possible Side Effects of Rybelsus?

Common side effects of Rybelsus include:

  • nausea,
  • abdominal pain,
  • diarrhea,
  • decreased appetite,
  • vomiting, and
  • constipation

What Are Possible Side Effects of Ozempic?

Common side effects of Ozempic include:

  • nausea,
  • vomiting,
  • diarrhea,
  • abdominal pain and constipation.

What Is Rybelsus?

Rybelsus (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

What Is Ozempic?

Ozempic (semaglutide) Injection is a glucagon-like peptide 1 (GLP-1) receptor agonist indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

What Drugs Interact With Rybelsus?

Ozempic may interact with other drugs. Tell your doctor all medications and supplements you use.

What Drugs Interact With Ozempic?

Ozempic may interact with an insulin secretagogue or insulin, and other oral medications taken at the same time. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Ozempic; it is unknown how it would affect a fetus. It is unknown if Ozempic passes into breast milk. Consult your doctor before breastfeeding.

How Should Rybelsus be Taken?

The initial dose of Rybelsus is 3 mg once daily for 30 days. After 30 days on the 3 mg dose, increase the dose of Rybelsus to 7 mg once daily.

How Should Ozempic be Taken?

The initial dose of Ozempic is 0.25mg once weekly. After 4 weeks, increase the dose to 0.5 mg once weekly. If after at least 4 weeks additional glycemic control is needed, increase to 1mg once weekly.