Prednisone vs. Prednisolone

• Are Prednisone and Prednisolonethe Same Thing?
• What Are Possible Side Effects of Prednisone?
• What Are Possible Side Effects of Prednisolone?
• What Is Prednisone?
• What Is Prednisolone?
• What Drugs Interact with Prednisone?
• What Drugs Interact with Prednisolone?
• How Should Prednisone Be Taken?
• How Should Prednisolone Be Taken?

Prednisone and prednisolone are corticosteroids indicated to treat or manage many conditions, including endocrine disorders, rheumatic disorders, collagen diseases, skin diseases, allergies, eye diseases, respiratory diseases, hematologic disorders, cancers, edematous states, and gastrointestinal diseases.

Brand names for prednisone include Deltasone, Rayos, and Prednisone Intensol.

Brand names for prednisolone include Omnipred, Pediapred, and Pred Mild.

Common side effects of Prednisone include:

• headache,
• nausea,
• vomiting,
• acne, thinning skin,
• weight gain,
• restlessness, and
• trouble sleeping.

Tell your doctor if you experience serious side effects of prednisone including

• severe allergic reactions (skin rash, itching, hives, swelling of your lips/face/tongue),
• mood changes or depression,
• eye pain or vision changes,
• fever,
• cough,
• sore throat,
• difficulty urinating, or
• high blood sugar (increased thirst, increased urination, confusion, or swelling of the ankles and feet).

Common side effects of Prednisolone include:

• infections,
• heartburn,
• trouble sleeping (insomnia),
• hunger,
• nausea,
• headache,
• dizziness,
• menstrual period changes,
• increased sweating,
• acne, and
• nervousness

Prednisone is a glucocorticoid indicated to treat or manage many conditions, including endocrine disorders, rheumatic disorders, collagen diseases, dermatologic diseases, allergies, ophthalmic (eye) diseases, respiratory diseases, hematologic disorders, neoplastic diseases (cancers), edematous states, and gastrointestinal diseases. Prednisone tablets are available in generic form.

Prednisolone is an adrenocortical steroid used for multiple conditions including endocrine disorders, rheumatic disorders, collagen diseases, skin diseases, allergies, eye diseases, respiratory diseases, blood disorders, cancers, edematous states, gastrointestinal diseases, and nervous system disorders, among others. The brand name of this medication is discontinued, but generic versions may be available.

Prednisone may interact with diuretics (water pills), blood thinners, cyclosporine, insulin or oral diabetes medications, rifampin, azole antifungals, or seizure medications.

Prednisone may also interact with antibiotics, anticholinesterase, isoniazid, bupropion, cholestyramine, cyclosporine, digitalis glycosides, estrogens (including oral contraceptives), barbiturates, ritonavir, indinavir, nonsteroidal anti-inflammatory drugs (NSAIDs), quetiapine, skin tests, thalidomide, and live or inactivated vaccines.

Following prolonged therapy, withdrawal of corticosteroids such as dexamethasone or prednisone may result in symptoms of the corticosteroid withdrawal syndrome including muscle or joint pain and feeling unwell (malaise).

Prednisolone may interact with other drugs. Tell your doctor all medications and supplements you use.

The initial dosage of prednisone may vary from 5 mg to 60 mg per day, depending on the specific disease entity being treated.

The initial dosage of prednisolone varies from 5 mg to 60 mg per day depending on the disease being treated.