Nurtec ODT vs. Ubrelvy

Nurtec ODT (rimegepant) and Ubrelvy (ubrogepant) are calcitonin gene-related peptide receptor antagonists used for acute treatment of migraine with or without aura in adults.

Side effects of Nurtec ODT and Ubrelvy that are similar include nausea.

Side effects of Nurtec ODT that are different from Ubrelvy include hypersensitivity reactions (including shortness of breath and severe rash).

Side effects of Ubrelvy that are different from Nurtec ODT include drowsiness and dry mouth.

urtec ODT may interact with strong and moderate CYP3A4 inhibitors, strong and moderate CYP3A inducers, and inhibitors of P-gp or BCRP.

Ubrelvy may interact with ketoconazole, itraconazole, clarithromycin, verapamil, cyclosporine, ciprofloxacin, fluconazole, fluvoxamine, grapefruit juice, rifampin, phenytoin, barbiturates, St. John's wort, quinidine, carvedilol, eltrombopag, and curcumin.

Common side effects of Nurtec ODT include:

• nausea and
• hypersensitivity (including shortness of breath and severe rash)

Common side effects of Ubrelvy include:

• nausea,
• drowsiness, and
• dry mouth

Nurtec ODT (rimegepant) is a calcitonin gene-related peptide receptor antagonist used for acute treatment of migraine with or without aura in adults.

Ubrelvy (ubrogepant) is a calcitonin gene-related peptide receptor antagonist used for the acute treatment of migraine with or without aura in adults.

Nurtec ODT may interact with other medicines such as:

• strong CYP3A4 inhibitors,
• moderate CYP3A4 inhibitors,
• strong and moderate CYP3A inducers, and
• inhibitors of P-gp or BCRP.

Tell your doctor all medications and supplements you use.

Ubrelvy may interact with other medicines such as:

• ketoconazole,
• itraconazole,
• clarithromycin,
• verapamil,
• cyclosporine,
• ciprofloxacin,
• fluconazole,
• fluvoxamine,
• grapefruit juice,
• rifampin,
• phenytoin,
• barbiturates,
• St. John's wort,
• quinidine,
• carvedilol,
• eltrombopag, and
• curcumin

Tell your doctor all medications and supplements you use.

The recommended dose of Nurtec ODT is 75 mg taken orally, as needed.

The recommended dose of Ubrelvy is 50 mg or 100 mg taken orally, as needed. If needed, a second dose of Ubrelvy may be administered at least 2 hours after the initial dose.