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Definition of Homogentisate 1,2-dioxygenase

Medically reviewed by Min Clinic Staff | Updated: January 2026

Homogentisate 1,2-dioxygenase: The enzyme encoded in the HGD gene. Mutation of HGD \causes the genetic disease alkaptonuria. Homogentisate 1,2-dioxygenase is also called homogentisate oxidase.