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Definition of Gliosis
Medically reviewed by Min Clinic Staff | Updated: January 2026
Gliosis: A process leading to scars in the central nervous system that involves the production of a dense fibrous network of neuroglia (supporting cells) in areas of damage. Gliosis is a prominent feature of many diseases of the central nervous system, including multiple sclerosis and stroke. After a stroke, neurons die and disappear with replacement gliosis.