Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Headache, rebound
Medically reviewed by Min Clinic Staff | Updated: January 2026
Headache, rebound: A headache experienced by someone who has taken pain relievers for migraines or other health conditions and has built up a tolerance for these medications. Often a rebound headache occurs right after the medication wears off. Treatment involves using the medication less frequently or switching to a different pain reliever.