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Definition of Cryoprotectant

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Cryoprotectant: A chemical component of a freezing solution used in cryopreservation to help protect what is being frozen from freeze damage. The chemical glycerol, for example, is commonly used as a cryoprotectant to protect frozen red blood cells.