Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Ascus
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
ASCUS: An acronym for Atypical Squamous Cells of Undetermined Significance. This term is used in the Bethesda System for reporting Pap smear findings, and indicates that some flat (squamous) cells look unusual and may or may not be pre-malignant or malignant.