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Definition of Dorian Gray effect

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Dorian Gray effect: Sudden aging, an abrupt change from seeming youthfulness to the reality and ravages of age, as can occur naturally or when the effects of plastic surgery and Botox treatments wear off. Named after "The Picture of Dorian Gray" (1890), the novel by Oscar Wilde, in which Dorian gives his soul to remain young while the painting of him grows old. Despite a life of dissipation and worse, Gray stays youthful in appearance. Instead, his portrait records his dissolute deeds, becoming a hideous mask. When Gray destroys the painting, his face turns into a replica of the portrait.