Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of DNS
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
DNS: On a prescription, Do Not Substitute. If a physician orders a particular drug and writes DNS on the prescription, that tells the pharmacist not to substitute a generic version or any other drug for the prescribed drug.