Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Chromosome, acrocentric
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
Chromosome, acrocentric: A chromosome that has its centromere located near one end of the chromosome. Humans have five pairs of acrocentric chromosomes. Down syndrome is due to an extra acrocentric chromosome (chromosome 21).