Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of Dicentric chromosome

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Dicentric chromosome: A chromosome that is abnormal in that it has two centromeres rather than one. Because the centromere is essential for chromosome division, a dicentric chromosome is pulled in opposite directions when the cell divides. This causes the chromosome to form a bridge and then break and be unstable.

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