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Definition of CCR5
Medically reviewed by Min Clinic Staff | Updated: January 2026
CCR5: A chemokine receptor found on monocytes and lymphocytes that serves as the coreceptor for HIV. HIV strains that use this coreceptor are referred to as R5 viruses. Polymorphisms in the coding and non-coding regions of the CCR5 gene influence the natural history of HIV infection. CCR5 (or CCCR5) stands for the CC chemokine receptor 5.