Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Macrocytic
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
Macrocytic: Literally, referring to any abnormally large cell; in practice, referring to an abnormally large red blood cell. For example, macrocytic anemia is characterized by abnormally large red blood cells. The opposite of macrocytic is microcytic.