Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Brittle bone disease
Medically reviewed by Min Clinic Staff | Updated: January 2026
Brittle bone disease: Osteogenesis imperfecta, not one but a group of genetic diseases, all of which affect collagen, a key component of connective tissue in tissues like bone, tendon and skin. All types of osteogenesis imperfecta result in fragile bones.