Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of Cascade

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Cascade: A sequence of successive activation reactions involving enzymes (enzyme cascade) or hormones (hormone cascade) characterized by a series of amplifications of an initial stimulus. In blood coagulation, for example, each enzyme activates the next until the final product, the fibrin clot, is reached.

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