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Definition of Alpha helix
Medically reviewed by Min Clinic Staff | Updated: January 2026
Alpha helix: The coiled structure of many proteins consisting of a single chain of amino acids stabilized by hydrogen bonds. The alpha helix was first proposed by Linus Pauling and Robert Corey in a brilliant series of paper in the early 1950s. It is also known as the Pauling-Corey helix. See also: Pauling, Linus.