Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Calor, dolor, rubor, and tumor
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
Calor, dolor, rubor, and tumor: Heat, pain, redness, and swelling. The four classical signs of inflammation, originally recorded by the Roman encyclopedist Celsus in the 1st century A.D.
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