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Definition of Blister beetle

Medically reviewed by Min Clinic Staff | Updated: January 2026

Blister beetle: A blister beetle is one of a number of beetles that have historically been used in dried or powdered form for medicinal purposes to raise blisters on the skin. An example of a blister beetle is the so-called Spanish fly. All blister beetles are soft-bodied beetles and belong to the family Meloidae.