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Definition of Calcium deficiency
Medically reviewed by Min Clinic Staff | Updated: January 2026
Calcium deficiency: A low blood level of calcium (hypocalcemia), which can make the nervous system highly irritable, causing spasms of the hands and feet (tetany), muscle cramps, abdominal cramps, overly active reflexes, and so on. Chronic calcium deficiency contributes to poor mineralization of bones, soft bones (osteomalacia) and osteoporosis, and, in children, rickets and impaired growth.