Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Aspartate aminotransferase (AST)
Medically reviewed by Min Clinic Staff | Updated: January 2026
Aspartate aminotransferase (AST): Also known as serum glutamic oxaloacetic transaminase (SGOT), AST is an enzyme that is normally present in liver and heart cells. AST is released into blood when the liver or heart is damaged. The blood AST levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack). Some medications can also raise AST levels.